Berkeley Lab's Biological Systems & Engineering Division has an opening for a Analytical Chemist Postdoctoral Scholar. You will be part of the Metabolomics Group led by Edward Baidoo in the Technology division led by Paul Adams at the Joint BioEnergy Institute (JBEI). Under general supervision of the principal investigator, you will work as part of a team that utilizes novel and existing metabolomics technologies to characterize engineered biosynthetic pathways and small molecule bioproducts. The incumbent will be working closely with Biofuels and Bioproducts, Feedstocks, and Deconstruction divisions at JBEI to develop methods and applications for targeted and untargeted metabolomics.
What You Will Do:
Design and implement microbial metabolomic studies to further scientific research at JBEI.
Develop and improve upon analytical protocols (e.g., LC-MS and CE-MS), sample preparation protocols, and metabolomic data analysis workflows.
Run analytical assays (e.g., LC-MS and CE-MS) for targeted and untargeted metabolomic workflows.
Analyze and interpret bioanalytical data.
Troubleshoot problems with analytical instrumentation and protocols and sample preparation protocols.
Learn and implement new experimentation techniques.
Interact with Technology and other JBEI divisions to identify researcher needs and develop analytical tools to fulfill them.
Maintain laboratory notes, reports, and operating procedures.
Prepare research results for publications and for presentations at scientific and internal meetings.
Write and prepare manuscripts for scientific publications.
Additional Responsibilities as needed:
Automate metabolomic sample preparation protocols via liquid handling robots.
Integrate ‘Omics’ workflows (e.g., metabolomics and proteomics).
Assist in preparation of grant proposals.
What is Required:
PhD in Analytical Chemistry, Chemistry, Biochemistry or a related field within the last 3 years.
Excellent understanding of chemistry together with biology and biochemistry concepts.
Demonstrated expertise in mass spectrometric-based analytical methods development and data analysis (e.g., LC-MS, CE-MS, and GC-MS).
Demonstrated experience in analyzing experimental data.
Demonstrated expertise in generating workflows for targeted, quantitative, and untargeted metabolomic analyses.
Good understanding of other analytical detection techniques (e.g., UV-Vis, RI, FID, etc.).
Demonstrated expertise in metabolite sample preparation (microbial, plant, etc.).
Good problem-solving skills.
Demonstrated knowledge and understanding of metabolism and physiology.
Excellent analytical, organizational and multitasking skills.
Excellent written, interpersonal, and communication skills are required due to the highly collaborative and research support nature of the position.
Able and willing to learn and implement new experimentation techniques.
Rigorous attention to detail and proper adherence to SOPs.
A commitment to and demonstrated ability to perform collaborative research in an interdisciplinary team environment.
A demonstrated capability to quickly learn new fields of science.
Additional Desired Qualifications:
Knowledge of microbial metabolism and physiology is highly desirable.
Knowledge of and experience with microbial cell culturing and sample preparation is highly desirable.
Some knowledge of the analytical requirements for 13C Metabolic Flux Analysis (13C MFA) and isotope dilution mass spectrometry.
Some experience in coding (e.g., python programming or R) is desirable (but not necessary).
The posting shall remain open until the position is filled.
This is a full time, 2 years, postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 3 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.
Full-time, M-F, exempt (monthly paid) from overtime pay.
This position is represented by a union for collective bargaining purposes.
Salary will be predetermined based on postdoctoral step rates.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at Joint BioEnergy Institute (JBEI) — Bldg. 978, 5885 Hollis St., 4th floor, Emeryville, CA.
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law."
Internal Number: 86074
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.