Berkeley Lab's Biological Systems & Engineering Division has an opening for a Microbiology Project Scientist. This position will serve as a Microbiology Project Scientist to develop different approaches to study explore environmental plasmidome and leverage the data obtained to mine environmental plasmids for synthetic biology parts and devices, thus developing tools to genetically modify novel environmental bacteria with a special emphasis on gram positive strains.
What You Will Do:
Survey plasmidome data and develop a systematic method to identify novel plasmid parts of interest including plasmid origins.
Engineer a bacterial tool kit for genetic modification of bacteria.
Design a combinatorial library in combination with a high throughput screen to test for genetic transformation assaying hundreds of strains in parallel.
Identify and array strains of high interest to deploy the tool kit.
Characterizing the strains that were modified and optimize the genetic modification strategies.
Collaborate effectively with multiple PIs and researchers of the ENIGMA project to accomplish the goals of the project.
Publish in high impact peer review journals; contribute to scientific research papers and reports.
Present scientific results at international meeting.
Additional Responsibilities as needed:
Keep and maintain accurate and detailed records of all research and experiments performed.
Deploy DOE KBase tools for project mission.
Assist with preparations for funding applications, grants and proposals.
What is Required:
Extensive background in microbiology including procedures for maintaining and assaying axenic strains of hundreds of non-model environmental bacteria.
Proficiency standard molecular biological techniques, with demonstrated experience in developing methods (preferably high throughput) for genetic modification including natural transformation of bacteria.
Experience in next gen sequencing, optimizing and developing novel methods/ assays, data analysis, and phylogenetic analyses.
Proficient in using robotics and liquid handlers.
Proven capacity to do innovative and applied work.
Previously trained to handle samples from DOE super fund sites and to develop assays with RG2 microbes and hazardous waste.
Demonstrated ability to troubleshoot problems and recommend actions.
Advanced analytical, organizational, and record-keeping skills
Effective interpersonal, verbal and written communication skills, including public-speaking and presentation skills.
Demonstrated ability to work well independently as well as a part of a diverse team.
Additional Desired Qualifications:
Ph.D. degree in Molecular Biology, Biology, Biochemistry, Chemistry or a closely related discipline with 4-5 years of experience in microbiology, molecular biology or systems biology research and development, is highly preferred.
The posting shall remain open until the position is filled.
This is a full time, 2 years, term appointment with the possibility of extension or conversion to Career appointment based upon satisfactory job performance, continuing availability of funds and ongoing operational needs.
Full-time, M-F, exempt (monthly paid) from overtime pay.
Salary is commensurate with experience.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at Joint BioEnergy Institute (JBEI) — Bldg. 978, 5885 Hollis St., 4th floor, Emeryville, CA.
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law."
Internal Number: 85957
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.