Berkeley Lab's Biological Systems & Engineering Division has an opening for a Biochemistry Postdoctoral Scholar. The DOE funded Joint BioEnergy Institute (JBEI) is a multi-organizational research center comprising world-class resources and expertise located in Emeryville, California. The vision of JBEI is that bioenergy crops can be converted into economically-viable, carbon-neutral, biofuels and renewable chemicals currently derived from petroleum, and many other bioproducts that cannot be efficiently produced from petroleum. JBEI's mission is to establish the scientific knowledge and new technologies in feedstock development, deconstruction and separation, and conversion needed to transform the maximum amount of carbon available in bioenergy crops into biofuels and bioproducts. When fully scaled, JBEI's technologies will enable the production of replacements for petroleum derived gasoline, diesel, jet fuel, and bioproducts. To learn more, visit https://www.jbei.org/.
The Microbial and Enzyme Discovery Group at JBEI is seeking a postdoctoral scholar to join our team. The incumbent will be focused on discovering and understanding the microorganisms and enzymes involved in biological lignin depolymerization, and harnessing this understanding to develop customized enzyme systems capable of producing targeted lignin-derived intermediates at high yields. You will be responsible for developing robust recombinant protein expression systems for a wide variety of enzymes from bacteria. You are expected to have a strong background in biochemistry and molecular biology, including recombinant bacterial protein expression. You will also collaborate closely with scientists in the Biomass Pretreatment Group and the Feedstocks and Technology Divisions at JBEI, so the ability to work effectively in teams and strong communication skills are critical attributes.
What You Will Do:
Identify bacterial lignin deconstructing enzymes from bacterial isolates and microbial communities.
Develop expression strategies for recombinant expression of these lignin deconstructing enzymes.
Purification of recombinant enzymes.
Functional characterization of lignin modifying enzymes.
Develop robust analytical methods for monitoring lignin bond cleavage or lignin modifications as a function of enzyme activity.
Develop enzyme mixtures that can generate targeted lignin-derived intermediates from lignin streams produced by biomass pretreatment.
Assist with the development of funding proposals and preparation of manuscripts for publication.
Publish scientific papers in peer-reviewed journals and present findings at seminars and conferences.
Collaborate with other members of the group and across the Divisions at JBEI.
Additional Responsibilities as needed:
Prepare and assist with the development of patents.
Participate in group meetings and seminars.
Maintain an accurate and detailed scientific logbook of all experiments performed. Ensure that others could duplicate results.
What is Required:
A Ph.D. in biochemistry, chemical engineering, biochemical engineering, or molecular biology.
Extensive experience in recombinant protein expression, enzyme purification and enzyme characterization.
Demonstrated track record of publishing in the peer-reviewed scientific literature.
Strong interpersonal and communication skills.
Ability to work with guidance of principal investigator and collaborators as well as to conduct experiments independently, maintain appropriate records and manage data.
Experience with scientific journal writing submissions and ability to write above average reviews and articles for submission.
Additional Desired Qualifications:
Previous research experience with lignin depolymerizing and modifying enzymes.
Previous research experience in the field of lignin depolymerization and development of assays methods for detecting lignolysis products.
Experience with high-throughput enzyme assay development and enzyme mixture optimization.
The posting shall remain open until the position is filled.
This is a full time, 1 year, postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 4 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.
Full-time, M-F, exempt (monthly paid) from overtime pay.
This position is represented by a union for collective bargaining purposes.
Salary will be predetermined based on postdoctoral step rates.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at Joint BioEnergy Institute (JBEI) — Bldg. 978, 5885 Hollis St., 4th floor, Emeryville, CA.
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law."
Internal Number: 85660
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.