Berkeley Lab's Joint Genome Institute (JGI) Division has an opening for a Secondary Metabolite Scientist (Career-Track). Under the guidance of the JGI Secondary Metabolite Group Lead, you will design, lead and conduct the experimental approaches for investigating the biosynthesis of novel natural products from novel and previously characterized hosts using a variety of state-of-the-art experimental approaches and technologies that currently exist or will be developed at the JGI. A focus area will be Actinobacteria that are involved in plant-microbe and microbe-microbe interactions, and this research will contribute to deepen the understanding of the composition and roles of secondary metabolites in these interactions. You will work in close partnership with computational biologist(s) to predict and validate secondary metabolite biosynthetic gene clusters that will allow us to refine our methods for biosynthetic pathway prediction. This role will prepare and present research findings for publication and at international meetings. The position will report to the JGI Director who also serves as the JGI Secondary Metabolite Group Lead.
What You Will Do:
Design, develop and/or apply molecular biology and microbiology approaches to investigate the biosynthesis of novel secondary metabolites from a wide range of native hosts using state-of-the-art technologies e.g. CRISPR, DAP-Seq, synthetic biology, cell-free expression.
Prepare results for publication and make presentations at seminars and scientific meetings. Contribute to scientific research papers and reports.
Actively lead and/or participate in specific project types that include but are not limited to DAP-Seq, novel host engineering, and other functional genomics projects
Establish effective and productive collaborations with leading secondary metabolite researchers
Interface and communicate with JGI management and other JGI scientists
Independently provide creative problem solving and work with a larger group of analysts/scientist to address and resolve challenges, questions or issues.
Additional Responsibilities as needed:
Maintain an accurate and detailed notebook describing analysis performed and to ensure that all results can be duplicated by others.
Attend group meetings and present status reports and scientific findings.
Lead, mentor and train graduate students, technical staff and other group members as necessary.
What is Required:
Ph.D. in molecular biology, biotechnology, biochemistry or related scientific or technical field.
At least three years of relevant postdoctoral experience in computational and experimental analysis and investigations of secondary metabolites.
Demonstrated experience and expertise in the biology and physiology of Actinobacteria.
Demonstrated expertise in a wide range of molecular biology tools and microbiology approaches especially, methods specific actinobacteria.
Demonstrated the ability to conduct and perform individual and collaborative research and effectively interact with a broad/diverse range of colleagues with tact and diplomacy.
Effective problem-solving, decision-making, organizational and analytical skills.
Experience with advanced data analysis, including integrating data from multiple OMICS technologies for visualization and statistical analysis
Demonstrated the ability to work independently and assist with the preparation of research data, trends and information for presentations within the principal investigator's lab.
Experience in preparing information for publications, presentations, seminars and scientific meetings.
Additional Desired Qualifications:
Experience in supervision or management of research staff
The posting shall remain open until the position is filled.
This is a full time, two year, career-track term appointment that may be renewed to a maximum of five years and that may be converted to career based upon satisfactory job performance, continuing availability of funds, and ongoing operational needs.
Full-time, M-F, exempt (monthly paid) from overtime pay.
Salary is commensurate with experience.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at DOE Joint Genome Institute (JGI) — 2800 Mitchell Dr., Walnut Creek, CA.
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law."
Internal Number: 84696
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.